Actilyse 50mg Injection (Alteplase)
Actilyse 50mg Injection contains alteplase, a medicine known as a thrombolytic or “clot-busting” agent. It works by activating a natural substance in the body that breaks down fibrin, the protein that holds blood clots together. By dissolving the clot, it restores blood flow through a blocked vessel. Actilyse uses include the emergency treatment of heart attack, acute ischaemic stroke, and life-threatening blood clots in the lungs (pulmonary embolism), and it is given only in a hospital or emergency setting under close medical supervision.
Description
Actilyse 50mg Injection Uses
- Emergency treatment of heart attack caused by a blood clot
- Treatment of acute ischaemic stroke (a stroke caused by a clot), within a strict time window
- Treatment of life-threatening blood clots in the lungs (pulmonary embolism)
- Used to restore blood flow by dissolving a clot blocking a vessel
- Administered by emergency and specialist medical teams
How Actilyse Is Given
Actilyse is not a self-administered medicine. It is given only in a hospital or emergency setting by trained medical staff, as a controlled intravenous infusion, often with part of the dose given as an initial injection followed by the rest over a set period. The dose and timing are calculated precisely by the treating team based on the condition, body weight, and how much time has passed since symptoms began. It must be given as early as possible, and only after serious bleeding has been ruled out.
Actilyse 50mg Injection Warnings
- The main risk is serious bleeding, including bleeding in the brain, which can be fatal
- Not to be used in people with active internal bleeding or a recent stroke, major surgery, or serious head injury
- Not suitable for people with very high uncontrolled blood pressure or certain bleeding disorders
- Time-critical, particularly in stroke, where it must be given within a strict window
- The treating team carefully weighs the benefit against the bleeding risk in every case
- Used only where emergency monitoring and support are available
Actilyse 50mg Injection Precautions
- Given only under close supervision in a hospital or emergency setting
- The patient is monitored continuously for bleeding and for response to treatment
- A full medical history, including recent surgery, injury, or bleeding, is reviewed first
- Blood pressure is checked and controlled before and during treatment
- Other medicines that affect clotting are used only with great care around treatment
- Requires proper storage and preparation by the hospital pharmacy
Actilyse 50mg Injection Side Effects
- Bleeding, ranging from minor bruising at the injection site to serious internal bleeding
- Low blood pressure
- Nausea and vomiting
- Fever
- Irregular heartbeat (particularly when treating a heart attack, as blood flow returns)
- Serious effects, such as bleeding in the brain, a severe allergic reaction, or major internal bleeding, are medical emergencies managed by the treating team
Storage Instructions
- Store below 25°C, protected from light, in the original carton
- Do not freeze
- Once reconstituted, use within the period advised by the manufacturer
- Handled, prepared, and stored only by the hospital pharmacy
- Keep out of the reach of children
Packaging and Quantity
Available as a 50mg vial of powder with solvent for reconstitution.
Prescription Requirement
Actilyse is a specialist, hospital-only emergency medicine. It is supplied strictly for use by trained medical teams under close supervision and is not dispensed for personal or home use.
Frequently Asked Questions about Actilyse 50mg Injection
What is the price of Actilyse 50mg Injection in Pakistan?
The price of Actilyse 50mg Injection in Pakistan varies as it is an imported emergency medicine. At Delta Pharmacy it is supplied only against a valid prescription for use in a medical setting.
Is Actilyse 50mg Injection available in Pakistan?
Yes, Actilyse 50mg Injection is available in Pakistan through hospital and specialist pharmacy supply, dispensed for use by medical teams.
What is Actilyse 50mg Injection used for?
It is used in emergencies to dissolve blood clots in heart attack, ischaemic stroke, and serious clots in the lungs, restoring blood flow.
Why must Actilyse be given quickly?
Because it works by dissolving a fresh clot, it is most effective when given early, and in stroke it must be given within a strict time window to be both safe and useful.
Disclaimer
This information is provided by Delta Pharmacy for general awareness only and is not a substitute for professional medical advice. Actilyse (alteplase) is an emergency hospital medicine given only by trained medical teams. Always seek immediate medical care in an emergency, and consult your doctor for any health concerns.
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